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MIC + B12 (Injectable)
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MIC + B12 Blend: Metabolic Cofactors for Fat Metabolism and Energy
Methionine, inositol, choline, and B12 in one weekly injection that supports the metabolic pathways behind fat use and energy production.
MIC + B12 is a combination injection of methionine, inositol, choline, and vitamin B12. These four are cofactors your liver and metabolic system use to process fat, support energy production, and maintain healthy cellular function. Most people use it as part of a weight-loss protocol or to support energy and metabolic health alongside lifestyle work.
Physician-prescribed · Compounded by licensed US pharmacies · Multi-cofactor blend · Ongoing care team support
Methionine, Inositol, Choline, B12 (MIC + B12 blend): Methionine is an amino acid central to methylation and liver detoxification. Inositol supports insulin signaling and is involved in metabolic regulation. Choline is essential for fat metabolism and the integrity of cell membranes. B12 is required for energy production at the cellular level. As a compounded blend, MIC + B12 supports metabolic pathways that are commonly bottlenecked in people working on weight loss or energy.
Best for: Adults on a weight-loss protocol who want metabolic cofactor support, or those looking for energy and metabolic optimization alongside diet and exercise.
Not recommended for: Anyone with cobalt allergy or Leber’s hereditary optic neuropathy, and people with hepatic encephalopathy (high methionine concerns).
Most common side effects are mild injection site reactions, transient flushing, and occasional headache or nausea. Allergic reactions are rare.
¹ B12 component restores B12 status in deficiency Stabler SP. Vitamin B12 Deficiency. New England Journal of Medicine, 2013;368(2):149-160. → PubMed
² Lipotropic components have biochemical roles in lipid metabolism Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Current Opinion in Gastroenterology, 2012;28(2):159-165. (Mechanistic role only; not evidence of weight-loss efficacy from injection.) → PubMed
³ Compounded under federal compounding oversight US FDA, Human Drug Compounding resource. (No FDA-approved lipotropic injectable exists for weight management; adequately controlled randomized trials demonstrating added weight loss are lacking.) → FDA
How it Works With EHRX
The entire process is online. No waiting rooms. Just straightforward, medically guided care.
Step 1
Choose your treatment and complete checkout
You'll receive a confirmation email with next steps.
Step 2
Complete a brief medical consultation
Check your email for a link to a short intake form and link to a virtual consult with a licensed physician.
Step 3
A licensed provider reviews your consultation
If approved, your prescription is written and sent to the pharmacy. If not, you receive a full refund.
Step 4
Your pharmacy ships within 3–5 business days
Your medication is shipped directly to your door in temperature-controlled packaging.
What to know before you start.
MIC + B12 (Injectable) is a compounded medication prepared by a licensed pharmacy for individual patient use.
It has not been reviewed by the FDA for safety or efficacy, and is prescribed based on the clinical judgment of a qualified healthcare provider. Compounded drugs are permitted to be prescribed but are not FDA-approved for safety and efficacy.
Clinical Evidence
MIC injections have been used for decades in weight-loss protocols, primarily as adjunctive support to diet and exercise rather than as a standalone weight loss intervention. Each component plays an established role in metabolic biochemistry. (Source: Mahan & Escott-Stump, Krause’s Food & The Nutrition Care Process, 2024)
Frequently Asked Questions
We aim to provide absolute clarity regarding your biological data and personalized wellness protocols.
Weekly subcutaneous or intramuscular injection.
Energy effects often appear within 1 to 2 weeks. Metabolic effects build alongside diet and exercise work over weeks to months.
MIC supports the metabolic pathways involved in fat processing and works best alongside diet, exercise, and (often) GLP-1 therapy as part of a comprehensive plan.
Not typically required.
You won’t be charged for the medication.
Compounded versions are typically paid out of pocket.
Yes, at any time before your next shipment, with no long-term commitment.
Initial check-in at 4 to 8 weeks, then on a recurring cadence.
Yes. MIC + B12 is commonly used alongside semaglutide or tirzepatide protocols.
The next generation
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Dual-incretin metabolic support — personalized to you.
